Proteasome Endopeptidase Complex

A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.

Also Known As:

Proteasome; Multicatalytic Endopeptidase Complex; 20S Proteasome; Ingensin; Macropain; Macroxyproteinase; Multicatalytic Proteinase; Prosome; Complex, Multicatalytic Endopeptidase; Complex, Proteasome Endopeptidase; Endopeptidase Complex, Multicatalytic; Endopeptidase Complex, Proteasome; Proteasome, 20S; Proteinase, Multicatalytic

Macromolecular Substances: 97
- Multiprotein Complexes: 125
  - Multienzyme Complexes: 8
    - Proteasome Endopeptidase Complex: 7107
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Proteasome Endopeptidase Complex: 7107
  - Multienzyme Complexes: 8
    - Proteasome Endopeptidase Complex: 7107

J R Bennink Selected Research

J R Bennink Research Topics

Disease

Drug/Important Bio-Agent (IBA)